重症急性胆管炎后多器官衰竭的危险因素分析

Multiple organ failure associated with svere acutecholangitis: analysis of risk factors

分析了２００例重症急性胆管炎（ＡＣＳＴ）及其中７０例并发多器官衰竭（ＭＯＦ）病例的临床资料，旨在研究重症急性胆管炎并发ＭＯＦ的危险因素。结果发现：早期休克、营养不良、肺部感染、败血症及长期胆道梗阻等病例的ＭＯＦ发生率明显增高（Ｐ＜０．０５）。作者认为早期监护高危患者和综合治疗是降低ＭＯＦ病死率的关键。

To detect the clinical course and possible patho-genetic factors of multiple organ failure(MOF) after se-vere acute cholangitis we investigated retrospectively 200patients with acute cholangitis and 70 cases of MOF a-mong them. The statistic data showed that the incidenceof MOF markedly increased in the cases of early circula-tory shock, malnutrition,pulmunary infection,sepsis andlong term biliary duct obstruction(P< 0.05 ).The au-thors suggest that early intensive care of high risk pa-tients and combined treatments are key factors of reduc-ing the mortality of MOF.