摘要
按滴眼液制剂要求，制备０．３％环丙沙星滴眼液，并建立紫外分光度法测定滴眼液中环丙沙星的含量，检测波长２２７ｎｍ，标准曲线的线性范围２～６ｍｇ／Ｌ（ｒ＝０．９９９９），平均回收率为９９．９６％，相对标准偏差为０．５２２７％，初步考察了该滴眼液的稳定性，结果表明，该滴眼液对热稳定。
Ciprofloxacin eye drops were preparaed and a spectrophotometric method for determination of ciprofloxacin in eye drops at wave length 277nm was es-tablished. The method has a linear range of 2.0 to 6. 0mg/L(r=0.9999),a average recovery of 99. 96%and a RSD of 0.5227%。 The result of its preliminary stability study showed that the preparation is stable to heat.
出处
《中国新药杂志》
CAS
CSCD
1995年第3期40-41,共2页
Chinese Journal of New Drugs
关键词
环丙沙星滴眼液
制备
含量测定
稳定性
Eye drop Ciprofloxacin Preparation determination Stability
