凯福隆治疗严重感染的疗效与安全性

EFFICACY AND SAFETY OF CLAFORAN IN THE TREATMENT OF SEVERE INFECTIOUS DISEASES

观察了应用凯福隆（即头孢氨噻肟）治疗３０例感染性疾患的疗效与安全性。结果表明：在其中可评价疗效的２９例（包括败血症及感染性休克１１例、下呼吸道感染８例、化脓性脑膜炎４例及其它感染病６例）中，凯福隆的临床有效率为９３．１％，细菌清除率为８９．５％；在可评价安全性的３０例（其中１例在用药２４ｈ后出现皮疹而换药，未评价疗效）中，６例发生了轻度不良反应，包括腹泻３例、药疹２例及药物热１例。

aduIt patients with infectious diseases including bacterial sep-ticemia or septic shock(n=11),pneumonia(n=8),purulent meningitis(n=4)andother infections(n=6) have been treated with claforan. The resuIts showed that thedrug has a clinical efficacy rate of 93.1%, bacterial eradication rate of 89.5%and amild ADRs in 6/30 patients including diarrhea(3 cases),skin rash(2 cases)andfever(1 case)。