含米托蒽醌的联合化疗方案治疗难治性复发性急性白血病

TREATMENT OF REFRACTORY AND RELAPSED ACUTE EUKEMIA WITH A REGIMEN OF MITOXANTRONE IN COMBINATION WITH OTHER DRUGS

应用含米托蒽醌的联合化疗方案治疗难治性及复发性急性白血病１８例。急淋７例（Ｌ１１例，Ｌ２６例），急非淋１１例（Ｍ２３例，Ｍ４３例，Ｍ５４例，Ｍ６１例）。完全缓解率５５．６％，部分缓解率１１．１％，，总有效率６６．７％。含米托蒽醌的联合化疗方案对难治、复发性急性白血病具有疗效高、副反应小的优点，是目前较理想的化疗方案。

patients with refractory and relapsed acute leukemia were treated with a regimen of mitoxantrone in combination with other drugs, with a complete remission rate of 55.6%, a partial remission rate of 11.1%and a ef-fective rate of 66.7%. Therefore,mitoxantrone is an effective drug for treatment of refractory and relapsed acute leukemia.