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微波热调节肢体慢性淋巴水肿免疫紊乱的实验研究 被引量:9

ABSTRACTEXPERIMENTAL STUDY ON MICROWAVE REGULATING IMMUNOLOGICAL DISOR-DER IN CHRONIC LYMPHEDEMA PATIENTS
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摘要 对20例肢体慢性淋巴水肿患者,在烘绑治疗前后,取外周血,用直接荧光标记单克隆抗体染色技术和流式细胞仪法检测T细胞亚群和HLA-DR表型变化,并与正常健康人对照,结果表明:肢体慢性淋巴水肿患者外周血CD_4明显下降,CD4/CD_8比值明显下降(P<0.01),HLA-DR水平增高。患者经微波烘疗两疗程后,CD_4/CD_8比值明显提高,CD_4明显增高,HLA-DR和CD_8HLA-DR明显下降。提示微波对肢体慢性淋巴水肿除热作用外,有明显的免疫调节生物效应。 wenty patients with chronic lymphedema had been treated by microwave heating . T-lym-pocyte subpopulation and HLA-DR phenotype of peripheral blood in patients with lymphedema were examined by using dual colour flow cytometry before and after treatment. We found that CD4 (Thelpte/inducer)in chronic lymphedema decreased significantly(P<0.01 ).HLA-DR in-creased signifieantly P<0.05).After the mierowave treatment,the CD4,CD4 /CD8 ratio in-creased significantly;HLA-DR, HLA-DR+ CD lymphocyte reduced.It was clear that mi-cruwave could regulate the immunological disorder of lymphedema patients.
出处 《中国修复重建外科杂志》 CAS CSCD 1995年第2期88-90,共3页 Chinese Journal of Reparative and Reconstructive Surgery
关键词 肢体 淋巴水肿 微波 T细胞亚群 Lymphedema,Mierowave T-lymphocyte Subpopulation。
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