摘要
对20例肢体慢性淋巴水肿患者,在烘绑治疗前后,取外周血,用直接荧光标记单克隆抗体染色技术和流式细胞仪法检测T细胞亚群和HLA-DR表型变化,并与正常健康人对照,结果表明:肢体慢性淋巴水肿患者外周血CD_4明显下降,CD4/CD_8比值明显下降(P<0.01),HLA-DR水平增高。患者经微波烘疗两疗程后,CD_4/CD_8比值明显提高,CD_4明显增高,HLA-DR和CD_8HLA-DR明显下降。提示微波对肢体慢性淋巴水肿除热作用外,有明显的免疫调节生物效应。
wenty patients with chronic lymphedema had
been treated by microwave heating . T-lym-pocyte subpopulation and HLA-DR phenotype of
peripheral blood in patients with lymphedema were examined by using dual colour flow
cytometry before and after treatment. We found that CD4 (Thelpte/inducer)in chronic
lymphedema decreased significantly(P<0.01 ).HLA-DR in-creased signifieantly P<0.05).After
the mierowave treatment,the CD4,CD4 /CD8 ratio in-creased significantly;HLA-DR, HLA-DR+ CD
lymphocyte reduced.It was clear that mi-cruwave could regulate the immunological disorder of
lymphedema patients.
出处
《中国修复重建外科杂志》
CAS
CSCD
1995年第2期88-90,共3页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
肢体
淋巴水肿
微波
T细胞亚群
Lymphedema,Mierowave
T-lymphocyte
Subpopulation。