摘要
用伪结核棒状杆菌人工感染60只实验小鼠。3周后,分别用利福平和青霉素等药物对其中存活的36只小鼠进行了治疗试验;同时检测了这2种药物向小鼠脓肿病灶内的穿透性。结果发现利福平对伪结核棒状杆菌导致的脓肿具有较强的穿透作用,连续用药一定时间后,能够彻底杀死脓肿病灶内的病原菌;而青霉素则不能穿透该脓肿的包膜,因此不能对其中的病原菌发挥有效的杀灭作用。
Caseous Lymphadenitis was experimentally induced to sixty mice by inoculating Corynebacterium Pseudo tuber culosis. The therapeutic test with rifampicin and penicilin was began in the survived thirty six mice three weeks later. We had also examined the permeability of the two medicines to the abscess. The results showed that rifampicin could penetrate quickly to the abscesses and perish the bacteria in them if used continuously. But penicilin could not penetrate and therefore could not eliminate the becteria in the abscesses.
