血清T、FSH对男性青春期生长发育和性发育的影响

Effects of Serum Testosterone and Follicle-stimulating Hormone on pubetal Growth and Development and Sexual Development of Schoolboys

本文采用放射免疫分析法，对包头市160名10～16岁男学生的血清促卵泡成熟徽素（FSH）、睾酮（T）含量进行了测定，并分析了FSH、T与青春期生长发育及性发育的关系。结果表明：11岁以后T水平开始急剧增加，直到15岁接近成熟时趋于平稳。此时生长发育进入突增阶段，T与身高、体重、LBM是明显的正相关（P＜0．001），表明T对生长发育有促进作用，特别是对LBM的增加有促进作用。T含量与性征发育存在明显的正相关（P＜0．001），并随着性征发育而明显增加．直至成熟，表明T对性发育也有促进作用。FSH在13岁时明显增加，15岁达峰值，以后开始下降，同时还得出首次遗精年龄为14.01±0．86岁，FSH与首次道精年龄存在明显的正相关（P＜0.001），说明FSH与首次道格的发生有关。另外，FSH与生长发育和性发育存在明显的正相关（P＜0，001），与T的相关系数为0．5203（P＜0．001），表明FSH对生长发育及性发育的作用与T分泌增多有关。

We determined serum testosterone (T), folicle - stimulating hormone (FSH) by using 125 I-labelled radioimmunassay method(RIA) and analysed the relationship between T. FSH and pubertal development. The results showed that serum T inereased rapidiy with adolecent growth spurt from 11 to 15 years of age, then came up to stability. T was correlated mpitively with height, weight. LBM and sexual development(P < 0. 001). It was snggested that T had an improving role in pubertal development. especially in LBM. The content of serum FSH increased significantly at 13 years of age. reached peak at 15, then began to slow down. FSH also was eorrelated with the age of the boys first emission(P < 0. 001 ). On the other hand, FSH and pudertal development showed a positive correlation (P < 0. 001). The correlaton coefficient of FSH and T was 0. 5205 (P < 0. 001 ). It was showed that the effects of FSH on pubertal development had relation to the increase of T secretion.