精子输卵管内移植术的临床应用研究

Clinical Study of Sperm Intro-fallopian Transfer

为探索腹腔镜下治疗不孕症的新助孕技术，开展了精子输卵管内移植（ｓｐｅｒｍｓｉｎｔｒａ－ｆａｌｌｏｐｉａｎｔｒａｎｓｆｅｒ，ＳＩＦＴ）。选择育龄不孕妇女２９例，其中１８例为自然周期，１１例为超排卵周期。采用Ｂ超等方法监测卵泡发育。排卵前行腹腔镜检查，将制备后的精液注入输卵管内。２９例ＳＩＦＴ中，３例（１０．３％）当月妊娠（均为自然周期），术后半年妊娠率为３１．０％（９例），而“真正”原因不明的１５例中ＳＩＦＴ术后半年妊娠率为４６．７％。初步观察结果表明，在腹腔镜操作技术熟练的基础上，ＳＩＦＴ可作为简易、安全、经济、有效治疗不孕症的一种新的助孕方法。

To explore the new technique of assistant pregnancy,we transferred sperm into fallopian tubes by laparoscopy Via an operation named sperm intra-fallopian transfer(SIFT).Twenty-nine infertile women(eighteen patients in natural menstrual cycle group,the others in the group of stimulated ovulation cycle)had their fallicle development with B ultrasonic scanning monitored.Patients were examined by laparoscopy before ovulation,then prepared sperm was transferred into fallopian tubes.Amony twenty-nine patients who had SIFT ,three were pregnant in the operation month.The rate of pregnancy in operation month was 10.3%,The rate of pregnancy during six months after SIFT was 31.0%(9 cases).Amony fifteen patients with“real”unexplained infertility,the rate of pregnancy during six months after SIFT was 46.7%.This preliminary result,showed that on the basis of skilled technique of laparoscopy,SIFT is a new,simple,safe,ecnomic and effective method in treating infertility.