硝苯地平治疗房室阻滞的观察

EFFECT OF NIFEDIPINE ON PATIENTS WITH ATRIOVENTRICULAR BLOCK

继在硝苯地平治疗病态窦房结综合征研究之后，又进行硝苯地平用于治疗房室传导阻滞（ＡＶＢ）的观察。观察对象共１４例（Ⅲ度及高度ＡＶＢ共１２例，Ⅱ度Ⅱ型ＡＶＢ２例）。其中１０例ＡＶＢ恢复窦性心律，症状消失，并维持稳定，判断为有效。另４例无效，但其中３例症状未再出现。本结果提示硝苯地平对ＡＶＢ似具一定治疗作用。

Following 'Nifedipine in SSS study', the present study was conducted as a second trial of the serial therapeutic studies of nifedipine on bradyarrhymias. 14 patients (9 males, 5 females; 38-76 years old) with chronic or intermittent complete or second degree type 11 AVB were treated with nifedipine in a dose range of 90-180 mg/day. 10 patients showed restoraton to sinus rhythm with symptoms disappeared and maintainedstable were evaluated as effective, while 4 patients were considered ineffective in a follow-up of 3～7months, but syncope did not occur thereafter in 3/4 of the latter patients. The results revealed that nifedipine appeared to be effective and safe both in short-term and long-term use for patients with AVB. Shanghai Huang Pu District Central Hospital,Shanghai