摘要
系统地研究了等摩尔比的NBS和取代芳伯胺在无水DMF中的单溴代反应。研究表明,NBS-DMF系统对芳伯胺类进行单溴代,具有反应专一,收率高,操作方便,通用性较好等优点。
The reaction between equimolar N-bromosuccinimide(NBS) and some primary arylamines in dry dimethylformamide(DMF) was systematically studied and it was found that NBS in DMF was ideal for the monobromination of primary arylamines.
出处
《中国药物化学杂志》
CAS
CSCD
1995年第1期56-58,78,共4页
Chinese Journal of Medicinal Chemistry