摘要
以环己酮为起始原料经2,2,6,6-四氯环己酮制备N-苯基-2,6-二氯苯胺(双氯灭痛的中间体)的新工艺路线。工艺简单、产品质量好、"三废"少,可较大幅度降低成本。
The new process, by which N-phenyl 2,6-dichloronailine is prepared(an intermidiate for preparing dichlofenac sodium)from the starting material cyclonexanone through 2,2,6,6-tetrachlorocyclo-hexanone, is comparablely simple, with better quality of the product,less wastes and much lower costs.
出处
《中国药物化学杂志》
CAS
CSCD
1995年第3期211-212,225,共3页
Chinese Journal of Medicinal Chemistry
关键词
制药
工艺
研究
二氯苯胺
制备
Tetrachloroeyclohexanone
Dichlofenac sodium
N-phenyl 2,6-dichloronailine