摘要
铀促排药物研究Ⅵ.2,3-二羟基-5-甲氧羰基苄基胺羧酸酯的合成陈文致,谢毓元(中国科学院上海药物研究所,上海200031)铀化合物侵入人体可导致肾脏损伤[1],含铀粉尘在肺部沉积可引发肺癌[2].对铀的防护和解毒药物的研究,已引起药学工作者的关注,...
In searching for effective antidotes against uranium poisoning,a series of 2,3-dihydroxy 5-carbomethoxybenzylamino diacetic acid hemi-esters was synthesized. Preliminary animal tests showed that some of them were distinctly effective through the oral route.
出处
《中国药物化学杂志》
CAS
CSCD
1995年第4期274-275,278,共3页
Chinese Journal of Medicinal Chemistry
关键词
铀促排药
二羟基
甲氧羰基
苄基胺羧酸酯
合成
Uranium antidote
2,3-Dihydroxy-5-carbomethoxybenzylamino diacetic acid hemi-esters