摘要
比较了两种葡萄糖注射液生产工艺对分解产物5-羟甲基糠醛(简称5-HMF)含量的影响,用正交法考察了生产工艺中影响葡萄糖分解的主要因素。结果证实:在生产周期中受热时间长短,灭菌温度、时间,样品在消毒锅中放置的位置等均是影响葡萄糖分解产物5-HMF多少的主要因素。
The effects of the technological process of injecting solution of glucose on out-comel 5-hydrorylmethyl furfural were studied.The main factors affecting the solution of glu-cose in the productive process by using the right cross method included the length of time,thetemperature and time of killing bacteria,and the positive sample in the sterilizing cauldron etc.
出处
《中国药学杂志》
CAS
CSCD
北大核心
1995年第9期553-555,共3页
Chinese Pharmaceutical Journal
关键词
葡萄糖注射液
制药工艺
羟甲基糖醛
灭菌
injecting solution of glucose,5-HMF,spectrophotometry,orthogonal method