摘要
本研究应用氚—胸腺嘧啶核苷（￣３Ｈ－ＴｄＲ）体外渗入放射自显影技术，对４０只兔角膜碱性烧伤后新生的毛细血管进行标记。在光镜和扫描电镜下，显示新生毛细血管超微结构的改变。研究结果发现：新生毛细血管是由角膜缘处的毛细血管内皮细胞分裂、增生，形成新的毛细血管，伸展侵入角膜基质层内，形成毛细胞血管网，在扫描电镜下，可见新生毛细血管被增生的胶原纤维呈层所包围。
he kinetics of
endothelial cells during microvascular growth were studied by using a
model of alka-line cauterization-induced neovascularization of 40
rabbits cornea. Changes in DNA synthetic activity ofendothelial cells
during neovascularization were assessed by autoradiographic study of
￣3H-TdR incorpo-ration in vitro. Microscopic study demonstrated that
migration and redistribution of existing endothelialcells from the
limbal vessels enabled vascular sprouting and enlongation with
cellular proliferation.
出处
《中国医科大学学报》
CAS
CSCD
1995年第1期45-47,共3页
Journal of China Medical University
关键词
角膜新生血管
细胞动力学
碱性烧伤
角膜损伤
corneal neovascularization
autoradiography:cytokinetics
alkaline burn
