血清β　HCG、E2、P测定及E2／P在早期宫外孕诊断中的估价

The Evaluation of Serum Hormone Levels(βRCG,E2,P)and E2/P in Diagnosis of Early Ectopic Pregnancy

本文选择１９９２年１１月～１９９４年５月经我院妇科确诊宫外孕患者２７例为研究组，３３例正常宫内妊娠为对照组。两组均经临床检查、血绒毛膜促性腺激素（βＨＣＧ）测定及Ｂ超声检查确诊，宫外孕经腹腔镜或剖腹手术证实。以放射免疫法测定两组患者血清βＨＣＧ、Ｅ２（雌二醇）、Ｐ（孕酮）值并计算Ｅ２／Ｐ，数值均经统计学（ｔ检验）处理。结果在同期妊娠中，宫外孕组βＨＣＧ、Ｅ２和Ｐ明显低于对照组相应值（Ｐ＜０．０１），与文献报道相符，而Ｅ２／Ｐ明显高于对照组（Ｐ＜０．０１）。目前尚未见文献有类似报道。Ｅ２／Ｐ中Ｅ２高时，可能造成相对高雌素状态而引起卵管活动异常导致宫外孕。因此推测βＨＣＧ、Ｅ２、Ｐ多项测定并以Ｅ２／Ｐ值来判断宫外孕有一定诊断价值。

cases of ectopic pregnancies(gestational period:44±56)and 33 cases of normal pregnancies(gestatiorial period:44±5d)as control groups were studied in our hospita from November,1992 to May,1994.The levels of serum hormone (βHCG,E2,P)were measured in two groups by a radioimmunological method.Thhe results were compared.The values of βHCG,E2,and P in ectopic pregnancy group were significantly lower than in the control group(P<0.01).The E2/P levels in ectopic pregnancy group were significantly higher than in the control group(P<0.01).Our conclusion is that ectopic pregnancy may be due to the state of the higher E2 levels.