摘要
本实验以25%TBSAⅢ度烧伤狗为模型,观察输平衡盐溶液与配合输全血对烧伤休克复苏血液动力学的影响。结果表明,两组在恢复的时间和程度上明显不同。输血组在复苏后18小时CI即明显恢复;而平衡液组迟至22小时。24小时后,两组CI差异显著。CI的恢复主要与SI提高有关。另外,平衡液组可造成PAP较明显的升高,特别是在烧伤后48小时与伤前及伤后多点差异显著。我们认为,配合输血确可比单纯使用晶体取得更满意的复苏效果。
In dogs inflicted third-degree burns of 25%TBSA the hemodynamic changes were observed with resuscitation with whole blood (group A) or balanced saline solution (group B). The results showed that there were significant diffirenees in time and degree of recovery between two groups. In group A, the recvoery of cardiac index (CI) began after 18 hr of resuscitation, and it was delayed to 22 hr; in group B, 24 hr after the injury. Two groups showed significant differences in CI. The recovery in CI related mainly to stroke index. Moreover, group B animals showed higher pulmonary arterial pressure after injury. There was significant difference between the level at 48 hr and the pre-injury level. It could be concluded that resuscitation with whole blood did give more satisfactory resuscitation than pure crystalloid.
