血栓通治疗慢性肺心病急性加重期31例的疗效观察

Therapeutic Effect of Xueshuantong Injection in Chronic Cardiopulmonary Disease Combined with Acute Exacerbation Stage

目的:观察血栓通治疗慢性肺心病急性加重期的临床疗效。方法:选择符合诊断病例63例作为研究对象,采用随机单盲分组对照法,将63例患者分为加用血栓通注射液组(治疗组)31例和单纯西药治疗组(对照组)32例,进行疗效对比分析,7天为一疗程,分别观察两组治疗前后患者的血液流变学,血气分析,临床症状及体征的变化。结果:治疗组显效24例,有效4例,无效3例,总有效率90.3%;对照组显效15例,有效8例,无效9例,总有效率71.9%,两组总有效率比较差异有显著性(P<0.05)。结论:慢性肺心病急性加重期在常规治疗基础上加用血栓通可以明显提高疗效。

Objective:To investigate therapeutic effect of Xueshuantong Injection in chronic cardiopulmonary disease combined with acute exacerbation stage. Methods:63 cases that fit the diagnostic criteria were randomly divided into control group (n=32) and treatment group (n=31) with single blind method. Xueshuantong Injection were given to the treatment group while the control group only received western medicine. 7 days are as a course of treatment. Observe the patients' hemorheology, blood gas analysis, clinical symptom and sign prior and post treatment in each group. Results: In the treatment group, the excellent, effective and ineffective cases were 24,4 and 3, total effective rate 90.3%;In the control group, 15,8 and 9,total rate 71.9%. The total effective rate in the treatment group was higher significantly than in the control group (P<0.05). Conclusions:Xueshuantong Injection with the basis of conventional therapy is effective in treating chronic cardiopuhnonary disease (acute exacerbation stage).