鼻塞式持续气道正压通气及琥珀酸氢化可的松静滴治疗小儿重症毛细支气管炎疗效观察

Effect of Nasal Continuous Positive Airway Pressure and Intravenous Drip Hydrocortisone Sodium Succinate on Severe Bronchiolitis

目的:观察鼻塞式持续气道正压通气(NCPAP)呼吸支持及琥珀酸氢化可的松静滴治疗小儿重症毛细支气管炎疗效。方法:将60例重症毛细支气管炎患儿随机分为对照组25例和治疗组35例,对照组仅予常规治疗,治疗组另予NCPAP呼吸支持及琥珀酸氢化可的松静滴。比较两组治疗前、后患儿临床表现改善情况。结果:治疗组和对照组的三凹征、喘息、喘鸣音、咳嗽的消失时间分别为0.3 d、0.8 d、1.5 d、4.3 d和1.1 d、2.2d、3.3 d和5.5 d;P均<0.05。结论:应用NCPAP呼吸支持及静滴琥珀酸氢化可的松治疗重症毛细支气管炎患儿较常规治疗的疗效好。

Objective: To observe the effect of nasal continuous positive airway pressure (NCPAP) and intravenous drip Hydrocortisone Sodium Succinate on severe bronchiolitis.Methods:60 children with severe bronchiolitis were divided into the treatment group(n=35)and control group(n=25) randomly. The treatment group was given NCPAP therapy and Hydrocortisone Sodium Succinate Ⅳ drop based on the control group only regular treatment. Comparing the time on changes of clinical manifestation in the two groups. Results: The vanishing time of three depressions sign, gasping,stridor and cough in the treatment group and the control group were 0.3 d & 1.1 d, 0.8 & 2.2 d, 1.5 d & 3.3 d and 4.3 d & 5.5 d,all P<0.05. Conclusion: NCPAP and intravenous drip Hydrocortisone Sodium Succinate on severe bronchiolitis has better effect than regular treatment.