失重或模拟失重对微生物的生物学效应研究进展

Research progress of the effects of microgravity or simulated microgravity on microorganisms

目的 综述国内外关于失重或模拟失重对微生物生物学效应方面的研究进展.资料来源与选择国内外该领域公开发表的相关论著及综述.资料引用引用文献资料38篇.资料综合空间失重环境可诱导微生物生理生化和遗传性状发生变异,一些原本对人体和环境无害的微生物种群会在毒力、致病性、抗生素敏感性等方面发生改变.结论 利用微生物开展空间失重生物学效应的研究对于阐明失重环境下微生物生存和变异的机制、未来空间受控生态生保系统的建立、空间微生物安全监控及空间失重资源的合理利用等都有重要的理论和实际意义.

Objective To summarize the latest studies on the biological effects of microgravity or simulated microgravity on microorganisms in the world. Literature resource and selection The related published articles and reviews in the field. Literature quotation Thirty-eight references were cited. Literature synthesis Studies showed that microgravity environment of space could induce the variations of microorganisms on their physiological, biochemical and genetic characteristics.Some microorganism populations, those are originally unharmful to human body or environment, show variations on virulence, pathogenicity, sensitivity to antibiotics, etc. Conclusion Studies on the effects of microgravity on microorganisms have important theoretical and practical significance on clarifying the survival and mutation mechanism of microorganisms in microgravity, establishing the future's space controlled ecological life support system, monitoring the safety of microorganisms in the space and rationally utilizing microgravity resources.