驻闽某部一起钩端螺旋体病暴发的临床分析

Clinical analysis on an outbreak of leptospirosis in fujian provincial command

目的总结驻闽某部一起钩端螺旋体病暴发的临床特点,探讨其防治对策。方法对2008年8-9月住院的29例钩端螺旋体病患者临床资料进行分析,采用显微镜凝集试验检测抗体。结果 29名患者均为青年男性,临床表现为寒战、高热、头痛、呕吐、全身乏力,腰背酸痛,腓肠肌痛;结膜充血明显且无分泌物,腹股沟淋巴结肿大;有23名病人钩端螺旋体显微镜凝集试验阳性,均为秋季热血清群;9例病人出现后发症状。结论临床医生要结合流行病学特征和临床特点进行综合分析,掌握钩端螺旋体病及其后发症的诊断及治疗。

Objective To summarize the clinical characters of an outbreak of leptospirosis in Fujian Provincial Command,and discuss the corresponding strategy of prevention and treatment.Methods The clinical materials of 29 inpatients with leptospirosis treated from Aug.to Sept.2008 were retrospectively analyzed.Microscopic agglutination test (MAT) was performed in the serological detection.Results All the 29 patients were young male adults.Clinical manifestations were chill,high fever,headache,vomi-ting,malaise,back pain,calf muscle tenderness,and inguinal lymphadenopathy.The positive antibody rate among the patients was 86.27% (23/29) ,and the outcome of serogroup was Autumnalis.There was late complication of leptospirosis in nine patients.Conclusion Clinicians need to make a comprehensive analysis by both the epidemiologic and clinical features of leptospirosis for correct diagnosis and treatment.