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胆红素的神经毒性 被引量:12

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摘要 胆红素的神经毒性主要与血清中游离胆红素的浓度有关。游离胆红素在脑脊液和中枢神经系统的蓄积,与血脑屏障上的转运蛋白以及机体内环境等诸多因素的影响有关。并且游离胆红素不仅对星形胶质细胞和神经元有毒性作用,还会干扰神经突触之间的神经递质的传递,同时还会损坏线粒体,导致细胞能量代谢障碍以及细胞的凋亡。本文就胆红素的神经毒性作一综述。
出处 《临床军医杂志》 CAS 2010年第4期669-672,共4页 Clinical Journal of Medical Officers
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