猪空肠占位模型64层CT仿真内窥镜技术的可行性研究

Feasibility study of detection for simulated occupying lesions in porcine jejunum with a 64-MSCT virtual endoscopy

目的 研究猪空肠占位模型64层CT仿真内窥镜技术(CTVE)对小肠模拟占位显示的可行性.方法 制作4段新鲜离体猪小肠占位性病变模型,每段长约36 cm,每段用猪髂腰肌修剪制作6枚模拟占位(直径0.5 cm、1.0 cm、1.5 cm各2枚),4段共24枚.一端结扎封闭,另一端通过16F双腔气囊导尿管与注射器相连.在完全充气状态下进行64层CT检查.用轴位、MPR和CTVE技术观察,应用4分级法评价模拟占位的显示情况,并与模型进行比较.结果 4段猪小肠均充盈饱满,图像清晰.24个模拟占位,轴位结合MPR能全部显示,显示率为100%,其中2个直径为0.5 cm的模拟占位显示效果为Ⅰ级,其余22个模拟占位显示效果为Ⅲ级;CTVE能全部显示,显示率为100%,显示效果均为Ⅲ级.结论 用猪小肠模拟占位进行64层CT扫描是可行的,在充分的气体充盈状态下,MPR结合仿真内窥镜技术能清晰显示直径小至0.5 cm的模拟占位.

Objective To study the feasibility of detection for simulated occupying lesions in porcine jejunum with a 64-MSCT virtual endoscopy. Methods Four fresh porcine jejunum segments(each 36 cm in length)were cleaned and 6 occupying lesions were simulated on the mucous surface in each segment for total of 24 lesions. Their diameters were 0.5 cm, 1.0 cm and 1.5 cm. The segments were then tied on one end and the other end were connected to an injector through a double cavity-Foley catheter for gas filling. The porcine jejunum segments was scanned with a 64-MSCT scanner under complete gas filling. The date was analyzed at the workstation. The simulated occupying lesions were observed in axial imaging and MPR imaging and CTVE. A 4-class system was used to quantify the lesion display class(LDC). To compare the source and the pattern of simulated occupying lesions. Results The four porcine jejunum segments were well-filling and the imaging were clear. 24 of simulated occupying lesions were all detected by axial and MPR and the rate of detection was 100%, the class wereⅠin 2 lesions of 0.5 cm and Ⅲ in the rest 22 lesions. CTVE can display all 24 lesions and the rate of detection was 100%, the class were all Ⅲ. Conclusions The method of detectionof simulated occupying lesions in porcine jejunum with a 64-MSCT scanning were feasibility. The combining of MPR and CTVEis favourable for the display of small intestinal lesionsusing 64-MSCT under adequate gas filling.