硅胶支载氯磺酸催化以丙酮为酸组分的三组分“一锅法”Mannich反应

"One Pot Method" Mannich Reaction Catalyzing Three Components as Acid Component of Acetonewith Brimstone Acid-loaded on Silicon Rubber

用催化产率高、可回收再利用的硅胶支载氯磺酸催化丙酮做酸组分与芳香醛和芳香胺的三组分‘一锅法’Mannich反应。此方案具有催化产率高、条件温和、不污染环境和操作步骤简单等特点。

We used environmentally friendly catalyst-SiO2-OSO3H,instead of the traditional liquid acid as a catalyst,of three components one-pot Mannich reactions of the aromatic acid components for Acetone and aromatic aldehydes,aromatic amines.This catalyst is cheap,and easily prepared.Compared with the traditional catalyst,this catalyst has feature of simple work-up procedure,high yield,no pollution,recycle and reusability.