摘要
对羟基苯甲酸酯是目前被广泛使用于食品、化妆品和药品等的防腐抗菌剂。但近年来的研究显示,该类物质具有弱雌激素活性,可能是乳房癌和男性不育的诱因。开展对羟基苯甲酸酯在人体中的暴露评价,可以为流行病学和该类物质的风险评价提供基础数据。本文对对羟基苯甲酸酯的性质和用途,在体内的吸收和代谢,毒理学效应,在人体中的暴露水平及分析方法等进行了综述。
Parabens are widely used as preservatives in many foods,cosmetics and pharmaceuticals consumer products.They are known to have weak estrogenic activity and suspected of causing disease,such as women breast cancer and man infertility in recent years.The evaluation of the exposure to parabens can provide useful data for epidemiological study and risk assessment of the substances.The commonly properties,usages,and toxicology of parabens,absorption,metabolism,and the level of exposure of parabens in human,and analytic methods are reviewed in the paper.
出处
《环境与发展》
2011年第3期161-165,共5页
Environment & Development
