上矢状窦栓塞大脑髓静脉改变的SWI研究

The variation of medullary veins on susceptibility weighted Imaging after the superior sagittal sinus thrombosis

目的:利用磁敏感加权成像(SWI)技术探讨上矢状窦栓塞后大脑髓静脉的改变。方法:对10例上矢状窦栓塞患者和年龄、性别相匹配的10例健康志愿者行常规MRI、MRV和SWI,应用计算机后处理软件对SWI图像进行处理,得到校正后的磁矩图和相位图,将大脑髓静脉增多扩张脑白质区作为病变组、其对侧镜像正常脑白质区为对照组1,健康志愿者与病变组相同位置脑白质区为对照组2,分别测量相位值,进行比较,统计学分析采用单因素方差分析。结果:病变组选择髓静脉增多扩张脑白质区37处测得相位值为-0.571～0.104,平均-0.051;对照组1相位值为-0.047～0.079,平均0.010;对照组2相位值为-0.045～0.056,平均0.014;病变组相位值低于对照组1和对照组2,差异有统计学意义(P<0.001);对照组1和对照组2相比,二者无显著差异(P=0.790)。结论:磁敏感加权成像(SWI)能明显显示上矢状窦栓塞患者大脑髓静脉的增多、扩张,并可利用相位信息为其提供量化依据。

Objective:To evaluate the variation of medullary veins in the brain after the superior sagittal sinus thrombosis using susceptibility weighted imaging(SWI).Methods:Conventional MRI and MRV and SWI were performed in 10 patients with superior sagittal sinus thrombosis and 10 healthy volunteers.Gender and age were matched between the two groups.SWI images were analyzed by the computer processing software and the corrected phase images and magnitude images were obtained.One-way analysis of variance was used to compare the phase values of white matter areas with increased and expansion venous(lesion group) with the contralateral white matter areas(control group 1) and the same location of healthy volunteers(control group 2).Results:For the selected 37 white matter areas with increased and expansion medullary veins,the phase values are from-0.571 to 0.104,the average is-0.051.For the control group 1,the phase values are from-0.047 to 0.079,the average is 0.010.For the control group 2,the phase values are from-0.045 to 0.056,mean 0.014.The phase values of lesions are significantly lower than the control group 1 and group 2(P﹤0.001).There is no significant difference of phase values between control group 1 and group 2(P=0.790).Conclusion:The increase and expansion of medullary veins after the superior sagittal sinus thrombosis can be displayed by susceptibility weighted imaging(SWI) and quantitative information can be provided by the phase value.