建立传导性角膜成形术动物模型的体会

Realization of the animal model of conductive keratoplasty

目的:建立(conductivekeratoplas,tCyK)手术动物模型,为临床开展CK手术提供了实验数据和理论依据。方法:实验用猪6只,术前行裂隙灯检查,OrbscanII角膜地形图检查,DGH超声测量猪眼角膜中央和周边厚度,按CK手术操作常规建立CK手术模型。结果:猪眼角膜前后表面均成中央岛形,中央及周边厚度超过560μm,成功建立猪眼CK模型。结论:猪眼角膜与人眼形态结构相似,可以作为建立CK手术模型的动物。

AIM： To establish the animal model of CK and to provide the experimental data and theoretical foundation of CK clinical works. METHODS： Six experimental porcins （12 eyes） were examined by slit-lamp microscope, Orbscan Ⅱ corneal topography and DGH ultrasound. The model was established according to CK operation routine. RESULTS： The most common types of porcine corneas were island shaped, ones and the central and peripheral thicknesses were more than 560 μm. The model of CK was established successfully. CONCLUSION： Porcine cornea is similar to hominine cornea in form, which can be used to establish the CK model.