摘要
本文对316例新生儿进行佝偻病的前瞻性观察,在新生儿期、3月、6月及6岁的患病率分别为7.9％,31.8％,35.3％及44.3％。证实北京地区佝偻病发病很早.孕妇在孕后期每日服VD1000Iu,其血清25(OH)D_3水平明显高于不服VD者,表明预防佝偻病措施应从妊娠后期开始.在被观察的早期婴儿中2.9％患婴儿肝炎综合征.这些患儿合并佝偻病高达88％,提示在治疗婴儿肝炎综合征的同时要加强佝偻病的防治.
A prospective study of rickets morbidity in 316 neonates had been carried on from their birth. The data demonstrated that the morbidity of rickets at the infant period. 3 months, 6 months and 6 years of age were 7. 9% , 31. 8% , 35. 3% and 44. 3%,respectively, which identified that the onset of rickets appeared early. Furthermore, the results of observation showed that taking 1000 IU of vitamin D per day during the late gesta-tional period, the serum level of 25-(OH)D3 in the pregnant women was evidently higher than those of in non-taking women, which indicated that measures for preventing rickets should begin in the late gestational period. In addition, 2. 9% of the infants who suffered from infantile hepatitis syndrome were also observed in their early childhood ;among them, 88 per cent were also with rickets, simutatiously. This suggested that on treat of infantile hepatitis syndrome,it is neccessary to strengthen the management of the rickets.
