摘要
本文采用PCR-STR及基因分型技术,研究广西仫佬族183例无关个体9个STR位点的遗传多态性分布,建立仫佬族群体的遗传学数据库.经统计分析,在9个STR位点共检出70种等位基因,其频率分布在0.0027~0.5301之间;207种基因型,其频率分布在0.0055~0.338 8之间;平均杂合度为0.7298,平均多态信息总量为0.7016,累积个体识别力达0.999999999,累积非父排除率达0.999098.与不同民族比较结果显示:广西仫佬族与广西苗、回族及云南、北方各民族之间绝大多数基因座存在显著差异,而与广西壮族和湖南汉族之间绝大多数基因座均无差异.以上数据可为群体遗传学、法医学及人类学等研究提供重要的资料.
Using PCR-STR, the polymorphism distributions of nine STR loci were investigated in 183 unrelated Mulao individuals from Guangxi Province, and as part of this work the genetic database of Mulao population was established. There were 70 STR alleles and 207 genotypes were observed in the nine STR of the Mulao ethnic group with statistical frequencies ranging from 0. 0027-0. 5301 and 0. 0055-0. 3388 respectively. The average heterozygosity was 0. 7298 ; polymorphism information content was 0.7016; accumulative discrimination power was 0.999999999, and the probability of paternity exclusion was 0.999098. The result of a comparison between the Mulao and other ethnic groups showed that there were statistically significant differences between the Mulao and Miao, Hui minorites of Guangxi and the minorities of Yunnan and North China, but with there was no difference between the Mulao and Guangxi Zhuang and Hunan Han minorities. The obtained data can be useful for its application to genetics, forensic science and anthropology.
出处
《人类学学报》
CSCD
北大核心
2005年第3期215-220,共6页
Acta Anthropologica Sinica
基金
国家自然科学基金(30260044)资助