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肝功能不全对男性患者罗库溴铵药效学的影响 被引量:2

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摘要 罗库溴铵是非去极化肌肉松弛药,ED95约为300μg/kg,主要由肝脏摄取、肝-胆道排泄.动物实验显示在阻断肝脏血流的条件下,罗库溴铵的临床作用时间增加约3倍[1],因此肝脏功能损害对患者罗库溴铵药效学特性可能会产生影响,但目前对肝硬化尤其严重肝功能不全(Child C级)患者罗库溴铵药效学的研究较少.本研究拟观察静脉麻醉下拟行肝移植术男性患者罗库溴铵药效学的变化.
出处 《中华麻醉学杂志》 CAS CSCD 北大核心 2005年第7期557-558,共2页 Chinese Journal of Anesthesiology
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参考文献11

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