摘要
目的总结原发性腹膜后肿瘤(PRPT)临床诊断治疗经验,分析影响PRPT手术效果和预后的因素。方法同顾性分析解放军总医院600例PRPT的临床诊断、手术治疗、疗效和预后。结果600例PRPT中546例行手术,肿瘤全部切除326例(占59.7%),肿瘤部分切除192例,肿瘤未切除取活检28例。同时行联合脏器切除手术113例(占20.7%)。PRPT完全切除组的1、3、5年生存率分别为:90.5%、73.2%、53.6%,恶性PRPT部分切除组的1、3、5年牛存率分别为:70.6%、32.0%、5.7%(P<0.01)。Cox多因素回归分析显示:PRPT的局部复发、生存期与(1)肿瘤是否完伞切除;(2)肿瘤大小;(3)肿瘤细胞的分化程度明显相关。结论充分做好PRPT手术前准备,提高肿瘤完全切除率,是降低PRPT肿瘤复发,提高生存率和预后的关键。
Objective： To summarize the experience of management for primary retroperitoneal tumor （PRPT） and to analyze the factors influencing the outcome after operation. Methods： The data of 600 cases of PRPT in General Hospital of PLA were reviewed retrospectively. Results： Of 600 cases of PRPT, 546 were surgically treated. Among theme 369 were malignant and 177 benign. 366 cases were followed up for 1 month to 15 years. The 1-years 3-year, and 5-year survival rate in the patients subject to complete resection was 90.5%, 73.2% and 53.6%, respectively, and that in incomplete resection patients was 70.6%, 32.0%, 5.7% respectively （P〈0.01）. The Cox multi-various regression analysis revealed showed completeness of tumor resection, sex and histologic type were associated closely with local recurrence. Conclusion： Sufficient preoperative preparation and complete tumor resection play important roles for reducing recurrence and improving survival.
