摘要
①目的探讨急性肾衰竭并发多脏器功能障碍(MODS)病人血液净化治疗模式的选择及疗效.②方法应用间歇式血液透析(IHD)治疗急性肾衰竭并MODS病人22例,连续性肾脏替代(CRRT)治疗急性肾衰竭并MODS病人30例,比较其疗效.③结果IHD组7例存活,15例死亡;CRRT组16例存活,14例死亡.两组病人治疗前的尿素氮(BUN)、肌酐(Cr)、HCO3-、K+、pH值水平比较,差异均无统计学意义(t=1.05～1.83,P>0.05).CRRT组治疗后不同时间点的BUN、Cr、HCO3-、K+与pH水平均低于IHD组,差异有统计学意义(t=2.72～13.80,P<.05).CRRT组严重低血压、心绞痛、严重心律失常、心力衰竭的发生率低于IHD组,差异有统计学意义(x2=2.21～8.32,P<.05).④结论对于急性肾衰竭并MODS病人更宜行CRRT治疗.
Objective To study the therapeutic effect of different blood purification methods for acute renal failure（ARF） associated with multiorgan dysfunction syndrome（MODS）. Methods IHD and CRRT were applied in 22 and 30 ARF patients with MODS, respectively. The effects were compared between the two groups. Results In the IHD group, 15 patients died and seven were cured; while in the CRRT group, 16 survived and 14 died. No significant differences were found in BUN, Cr, HCO3^- , K^＋, or pH value between the two groups before the treatment（t=1. 05-1. 83,P〉0. 05）. After the treatment, BUN, Cr, HCO3^-, K^＋, and pH value in the CRRT group were lower than those in the IHDgroup（t=2.72 13. 80,P〈0. 05）. The incidence of severe hypotension, angina pectoris, serious cardiac arrhythmias, and cardiac arrest in the CRRT was lower in the IHD grouP（χ^2=2.21-8.32,P〈0.05）. Conclusion CRRT is more effective than IHD for ARF patients with MODS.
出处
《齐鲁医学杂志》
2005年第2期119-121,共3页
Medical Journal of Qilu
