苯那普利对不同程度肾性蛋白尿的疗效分析

Analysis of the effect of Benazepril in patients with different levels of renal proteinuria

目的 探讨苯那普利对不同程度肾性蛋白尿疗效的差异。方法 61例不同程度蛋白尿患者服用苯那普利20～30mg／d，观察12周，治疗前、后定期监测血压、尿蛋白、肝功能、肾功能及血钾。结果 尿蛋白〈3g／d的41例患者治疗后，33例转阴，3例有效，总有效率为88％；尿蛋白≥3g／d的20例患者治疗后，6例转阴，4例治疗有效，总有效率为50％。结论 苯那普利对不同程度肾性蛋白尿均有治疗效果，尿蛋白〈3g／d患者较≥3g／d者疗效更佳。

Objective To investigate the effect of P, enazepril in patients with proteinuria in different levels. Method 61 cases with proteinuria received P, enazepril 20-30 mg/d. The treatment las- ted for 12 weeks and the parameters of blood pressure, proteinuria, liver function, renal function and serum potassium were detected before and after treatment. Results After treatment, 33 cases turned to negative, 3 cases were effective and the total effective rate was 88% in 41 cases with 24-hour proteinuria excretion below 3.0g; 6 cases turned to negative,4 cases were effective and the total effective rate was 50% in 20 cases with 24-hour proteinuria excretion over 3.0g. Conclusions P, enazepril is an effective measure for patients with renal proteinuria in different levels, especially for those with 24-hour proteinuria excretion below 3. 0g.