摘要
通过灌服不同剂量姜黄素,测试了大鼠在疲劳运动后血清肌酸激酶(CK)、谷草转氨酶(SGOT)、谷丙转氨酶(SGPT)、乳酸脱氢酶(LDH)的活性和心肌、肝组织超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)活性和丙二醛(MDA)含量。旨在研究服用不同剂量姜黄素对大鼠由于运动导致不同组织自由基损伤的保护作用。结果表明,服用不同剂量姜黄素使大强度运动大鼠血清CK、SGOT、SGPT、LDH活性有不同程度的下降;大鼠心肌、肝组织SOD、CAT、GSH-Px活性都有不同程度的升高、MDA含量显著降低(p<0.05),并呈一定量效关系。结论:姜黄素对疲劳运动所致大鼠肝和心肌组织自由基损伤具有明显保护作用。
By taking the different dosage of Curcumin. Researched the activity of Creatine kinase (CK), Glutamic-pyruvic Transaminase (SGPT), Glutamin-oxalacetic Transaminase(SGOT), lactate dehydrogenase (LDH) in serum, and Superoxide dismutase (SOD), Glutathione peroxide(GSH-Px), Catalase(CAT)in the tissues of heart and liver. The results showed: Cur significantly decreased the activity of CK, SGOT, SGPT, LDH (p 〈 0.05), increased the activity of SOD,CAT, GSH-Px in the tissues of heart, liver,and decreased the content of MDA in liver(p 〈 0.05).The conclusion: Cureumin has the strong actions on enhancing antioxidant, clearing the free radicals and promoting the capability of exercise.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2005年第8期364-366,共3页
Food Science
关键词
姜黄素
运动
自由基
大鼠
Curcumin
exercise
free radicals
rat