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釉质基质蛋白诱导延迟再植牙牙周愈合的研究 被引量：1

The study of enamel matrix proteins (EMPs) on periodontal healin after delayed replantation of incisors in Beagle dogs
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摘要 目的:研究应用釉基质蛋白对延迟再植比格犬恒切牙牙周再生的影响。方法:选取3只比格犬的15颗干燥60min的切牙随机分为两组,实验组10颗牙根涂釉基质蛋白;对照组5颗牙根不涂釉基质蛋白,进行再植。8周后处死犬,每隔500!m切取5"m厚的横断切片作组织学观察。结果:与对照组相比,实验组牙再植后能显著地增加牙周膜性愈合的数量(P<0.001),并减少替代性吸收(P<0.001)。结论:釉基质蛋白能对延迟再植牙的牙周愈合有促进作用。 Objective： To evaluate the effect of enamel matrix proteims （EMPs） on periodontal healing after delayed replantation of permanent incisors in Beagle dogs. Methods： A total of 15 incisors of 3 Beagle dogs were selected for replantation after 60min drytime. Experimental group consisted of 10 roots that were coated with EMPs, the control group consisted of 5 roots that were replanted without EMPs. After 8 weeks, the dogs were killed and the roots were prepared for histological evaluation. About 5μ m thick cross-sections of the roots and surrounding tissue taken every 500μm were evaluated for healing. Results： The roots with EMPs showed significant increase in periodontal healing compared to roots without EMPs treatment （P〈0.001） and significant decrease in replacement resorption （P〈0.001）. Conclusion： The results suggested that EMPs enhances periodontal healing of delayed replantation.
作者 高旭 张苹 谭建国 冯海兰
机构地区 北京大学口腔医学院修复科
出处 《口腔颌面修复学杂志》 2005年第3期182-185,共4页 Chinese Journal of Prosthodontics
关键词 釉基质蛋白 牙周膜 延迟牙再植 牙根吸收 愈合 enamel matrix proteins （EMPs） periodontal ligament root resorption delayed tooth replantation healing
分类号 R782.12 [医药卫生—口腔医学]
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参考文献14

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二级参考文献10

  • 1Iqbal MK, Bamass N. Effect of enamel matrix derivative (EMDOGAIN) upon periodontal healing alter replantation of permanent incisors in beagle dogs.Dent Traumatol 2001:17 (1 ): 36 -45.
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同被引文献11

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口腔颌面修复学杂志
2005年 第3期

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