胺碘酮对VVI起搏后心房颤动发生率的影响

Effect of Amiodarone on Incidence of Atrial Fibrillation after VVI Pacemaker Implantation

目的观察胺碘酮对VVI起搏后心房纤颤发生率的影响。方法42例植入VVI型起搏器的缓慢型心律失常患者起搏后,分成2组A组为植入VVI起搏器患者进行常规治疗,共21例;B组为在植入VVI起搏器后,按标准方案给予胺碘酮治疗,共21例。术后所有患者分别于出院后第1、6、12、24、36个月进行随访。结果A组19例患者达到随访终点,8例(42.1%)发生慢性房颤;B组20例患者达到随访终点,3例(15.0%)发生慢性房颤。结论胺碘酮对植入VVI型起搏器患者心房颤动的发生有明显的抑制作用。

Objective ： To investigate the effect of amiodarone on incidence of atrial fibrillation after VVI pacemaker implantation. Methods：Forty-two patients with cardiac arrhythmia of slow type divided into two groups randomly after pacing impulse by VVI pacemaker. Group A （n=21） received regular treatment after VVI pacemaker implantation, while group B （n=21） received a standard treatment with amiodarone after operation. All patients accepted the following-up in the 1 st, 6 th, 12 th, 24 th, 36 th month respectively after discharged. Results： Nineteen cases in group A reached the end of follow-up, chronic atrial fibrillation occurred in 8 cases among them （42. 1%, 8/19）. Tweenty patients in group B accomplished the follow-up, chronic atrial fibrillation was observed in 3 patients （15.0%, 3/20）. Conclusion：Amiodarone can suppress the incidence of atrial fibrillation obviously after VVI pacemaker implantation.