非心脏胸外科手术对于血清CTnI的影响

Effect of non-heart thoracic surgery on serum CTNI

目的对照CK-MB结果,观察非心脏胸外科手术对于血清cTnI的影响。方法全部29例病人分成3组:胸腔镜组;肺手术组;食管手术组。术前、术后16￣18h、42￣48h、72h、术后1周各1次采取静脉血,测定血清cTnI及CK-MB,数据采用SPSS软件进行配对t检验及单因素方差分析。结果cTnI术后各时点与术前相比较差异无统计学意义,CK-MB在术后48h内数值明显升高,72h基本恢复正常;年龄,手术切口,手术时间,术中出血量,手术方式等因素对于CTnI组间及组内的影响均无统计学意义,以上因素对于CK-MB存在不同程度影响。结论血清cTnI在非心脏胸外科手术术中、术后受心外因素影响轻微,假阳性率低,具有可靠的心肌特异性。

[Objective] To observe the affects of non-heart thoracic operatrion on the serum CTNI with reference to CK-MB. [Methods] A total sample of 29 patients were divided into 3 groups： thoraeoseope; lung and esophageal .Phlebotomized before the preeedure and 16-18 hrs; 42-48 hrs; 72 hrs; one week after. Detected eTnI and CK-MB. The data was analyzed by SPSS software with paired-samples T Test and one-way ANOVA. [Results] The change of CTNI had no statistical significance when the postoperative results compared with preoperative resuits. The level of CK-MB in postoperative 48 hours increased obviously but turned down to normal level in 72 hours. The factors of age, operative incision, duration of operation, the hemorrhage volume in operation and the method of operation that affect the eTnI in intergroup and intragroup are not statistically significant. But the above factors affected the CK-MB more or less. [Conclusions] The serum CTNI could hardly be influenced by non-heart factors in perioperation of son-heart thoracic operation. With the low level of false positive rate, eTnI has a reliable myocardial characteristic.