ICU可调节人工晶体的初步临床研究

Preliminary clinical study of accomodative intraocular lens 1CU

目的评估1CU可调节人工晶体的安全性、有效性。方法23例(30只眼)老年性白内障患者行超声乳化手术并植入1CU可调节人工晶体,另外26例(35只眼)植入AR40e人工晶体。观察患者术后的裸眼远近视力、矫正远近视力、最佳矫正远视力下的近视力、调节幅度及手术并发症。结果随访3个月,两组的裸眼远视力、矫正远视力、矫正近视力差异无显著意义(χ2=1.626、1.490、0.136,P>0.05),1CU组的裸眼近视力和最佳矫正远视力下的近视力好于AR40e组(χ2=7.987,8.126,P<0.05)。动态检影法测得调节幅度1CU组(2.58±0.37)D大于AR40e组(1.46±0.25)D(t=14.334,P<0.001)。前房深度法测得调节幅度1CU组(1.22±0.38)D大于AR40e组(0.45±0.25)D(t=9.711,P<0.001)。结论1CU可调节人工晶体是安全有效的,能使白内障患者术后获得一定的调节力,提供良好的远近视力。但其远期效果还需更大样本、更长时间的研究。

Objective To evaluate the safety and effectiveness of accomodative intraocular lens ICU. Methods 23 patients （30 eyes） with age- related cataract underwent phacoemulsification and were implanted with ICU IOL while other 26 patients （35 eyes） were implanted with AR40e. The uncorrected and cor rected distant and near visual acuily, distance corrected near acuity, accomodative range and complications were observed. Results After follow- up period of 3 months, the uneorrected distant, corrected distant and corrected near visual acuity have no significant differences between two groups （X^2=1.626, 1.490, 0. 136, P〉0.05）. The uncorreeted near and distance corrected near visual acuity of ICU group are better than AR40e （X^2= 7.987, 8. 126, P〈0.05）. The retinoscopic aecomodative range is （2.58 ± 0.37） D in ICU group and （1.46±0.25） D in AR40e group （t=14.334, P〈0.001 ）. The accomodative range ealeulated by the anterior chamber depth is （ 1.22 ± 0.38） D in ICU group and （0.45 ± 0.25） D in AR40e group （ t = 9.711, P〈0.001）. Conclusions The ICU IOL is safe and effeetive. It can provide good distant and near visual acuity, but its longer effect is needed for further study.