摘要
目的研究内镜下乙酸染色对于诊断Barrett食管(Barrett'sesophagus,BE)的帮助。方法用喷雾管在24例患者食管远端喷洒1.5%乙酸5~10mL,随后喷洒自来水50mL并进行观察。结果以1.5%乙酸喷洒食管远端黏膜,开始食管黏膜和胃黏膜都变白,约2、3min后观察,食管鳞状上皮仍是白色,柱状上皮变成微红色,并且柱状上皮周边有白色边缘。结论乙酸染色可指导微小或不易辨别的BE上皮的活检,提高对BE的诊断率,这种方法安全、迅速、价廉。
[Objective] To study the improvement on diagnosis of Barrett esophagus with instillation of acetic acid. [Methods] In 24 patients, 5 to 10 mL of 1.5% acetic acid was sprayed onto the distal esophagus using a spray catheter, followed immediately by spraying 50 mL tap water. [Resultsl Initially, a whitish coloration developed in both esophageal and gastric epithelia with the 1.5% acetic acid sprayed onto the distal esophagus. After 2 to 3 minutes, the esophageal squamous mucosa remained white but the columnar epithelium became reddish. Barrett's epithelium was outlined by a white rim. [Conclusions] Acetic acid instillation enhances the ability to detect small or indistinguishable islands of columnar epithelium of BE and to obtain targeted biopsy specimens. This method is safe, rapid, and inexpensive.
出处
《中国内镜杂志》
CSCD
北大核心
2005年第8期799-800,803,共3页
China Journal of Endoscopy
关键词
乙酸
活检
BARRETT食管
诊断
instillation of acetic acid
biopsy
Barrett esophagus
diagnosis