早产儿光疗后低钙血症原因的探讨

Study on the hypocalcemia caused by phototherapy in preterm infants

目的探讨蓝光治疗早产儿高胆红素血症对血清钙的影响。方法将82例新生儿高胆红素血症患儿按胎龄分为足月儿及早产儿两组,足月儿47例,早产儿35例,测定光疗前后血清钙水平,比较两组低钙血症的发生率。结果足月儿和早产儿光疗后血清总钙和游离钙均下降(P均<0.01),早产儿低钙血症的发生率为63.0%,足月儿为25.5%,两组比较有显著性差异(P<0.01)。结论早产儿接受光疗时比足月儿更易发生低钙血症,光疗时应监测血钙浓度,胎龄<34周的早产儿宜常规补钙。

Objective To study the effect of phototherapy on serum calcium in preterm infants with hyperbilirubinemia. Methods 82 infants with hyperbilirubinemia were divided into two groups by gravidity time., preterm group and term group. Serum calcium was measured before and after phototherapy. The incidence of hypocalcemia was compared between the two groups. Results Total serum calcium concentration decreased after phototherapy in both groups. The incidence of hypocalcemia in preterm infants were significantly higher than that of term infants（ P 〈0.01）. Conclusion Preterm infants would get hypocalcemia easier than term infants while they are undergoing phototherapy , the concentration of serum calcium should be test during the phototherapy, preterm infants whose gestational age is smaller than 34 week should supplementary calcium ordinarily.