酒石酸泰乐菌素的体外抗病原菌活性测定

ASSAY OF THE ACTIVITY OF TYLOSIN TARTRATE AGAINST PATHOGENIC BACTERIA IN VITRO

本研究进行了国产酒石酸泰乐菌素在体外对几种常见病原自活性及最小抑菌浓度测定，并与进口酒石酸泰乐菌素进行对比。结果表明，国产酒石酸泰乐菌素对金黄色葡萄球菌，猪丹毒杆菌、多杀性巴氏杆菌、致病性大肠杆菌、鸡白痢沙门氏菌、嗜水气单胞杆茵和鸡败血支原体的ＭＩＣ（μｇ／ｍｌ）分别是４．８９，９．７７，９７．６６，１５６２．５，３１２５和０．０５，其中对鸡败血支原体最好，与有关文献报道基本一致，同时与进口酒石酸泰乐菌素有相似的抗菌谱及抗菌效力。

The activity against pathogentic bactetia in vitro and MIC of Tylosin tartrate(made in China)are studied andcompared with Tylosin tartrate(made in Amcrica)in this paper.We found that the MIC(μg/ml)of Tylosin tartratc(made inChina)versus several pathogenic bacteria,such as Staphylococeus aureus,Erysipclothrix rhuriopathiae,Pasteurella multocide,Pathogcie Escherichia coli,Salmonclla pullorum,Aeromonas hydrophila and Mycoplasma gallisepticum,is rspcctivcly 4. 89,9.77,97.66,1562.5. 3125,3125,0.05.M. gallisepticum has minimum MIC and highest susceptibility.The results thisresearch are in general agreement with the results reported by someliteratures.Our results suggest that Tylosin tartrate(made inChina)has similar antibacterial range and activity with Tylosin tartratc(made in AYmerical).