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抑郁症的神经生物学基础 被引量：13

Neurobiological basis of depression
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摘要 目前抑郁症的患病率呈上升的趋势,已成为危害人类健康的常见病。研究显示抑郁症有其神经生物学基础,本文结合近年来的研究进展,从中枢神经系统组织形态结构、中枢神经递质及其受体功能和神经内分泌功能这三个方面的变化,对抑郁症的发病机理作一介绍。
作者 张凌 毛玉婷
机构地区 华东师范大学生命科学学院
出处 《生物学教学》 北大核心 2005年第9期5-7,共3页 Biology Teaching
关键词 抑郁症 神经生物学 中枢神经系统 神经递质 生物学基础 组织形态结构 中枢神经递质 内分泌功能 人类健康 发病机理
分类号 G634.91 [文化科学—教育学]
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参考文献10

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  • 3Moore GJ, Bebchuk JM, Hasanat k, et al. 2000. Lithium increases Naspartate in the hrman brain:in vivo evidence in support of bcl -2's neurotrophic effects? Biological Psychiatry,48( 1 ) :1 ～ 8.
  • 4Sheline YI ,Wang PW,Gado MH ,et al. 1996. Hippocampal atrophy in recurrent major depression. Proceeding of the National Academy ofSciences,93(9):3908～13.
  • 5侯钢,张心保,陈珏,姚辉,张石宁,翟书涛.抑郁症患者中枢单胺类神经递质相互关系的对照研究[J].中国神经精神疾病杂志,2002,28(1):7-7. 被引量：16
  • 6Yatnam LN,Liddle PF,Shiah IS ,et al. 2000. Brain serotonin2 receptors in major depression: a positron emission tomography study. Archives of General Psychiatry,57 (9) :850～ 8.
  • 7Whale R,Clifford EM, ,Bhagwagar Z,et al. 2001. Decreased sensitivity of 5 - HT(ID) receptor in melancholic depression. The British Journal of Psychiatry,178:454 ～457.
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二级参考文献9

  • 1[1]Engstrom G, Alling C, Blennow K, et al. Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls. Eur Neuropsy-chopharmacol, 1999,9(5): 399.
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共引文献15

同被引文献114

引证文献13

二级引证文献82

生物学教学
2005年 第9期

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