摘要
采用改进的Troost法对97例正常人、116例原发性肝癌(PHC)、21例肝硬化、21例转移性肝癌、32例其它消化道恶性肿瘤、12例肝良性病变患者血清α-L-岩藻糖苷酶(AFU)活性进行了测定。结果PHC组血清AFU活性明显高于其它各疾病组,更高于正常人组(P<0.01)。对PHC诊断敏感性为75%,特异性为90.1%,在36例甲胎蛋白(AFP)阴性的PHC中,AFU阳性率为80.6%。AFU与AFP联合检测,可使PHC的诊断阳性率提高到93.9%。
The activity of serum alpha-L-fucosidase(AFU) in 116 patients with primary hepatic carcinoma(PHC), 21 hepatic cirrhosis,21 metastatic hepatic cancers,32 malignant cancers of digestive tract and 12 benign bepatic diseases and 97 normal subjects was determined with modified Troost method.The results showed that serum AFU activity in PHC patients was higher than that with other disease and markedly higher than in normal controls(P<0.01).In PHC patients,the sensitivity rate was 75%,specificity 90.1%.In 36 PHC patients in whom AFP was negative,the positive rate for AFU was 80.6%.The accuracy rate in PHCcombining positivity of AFU and AFP was 93.9%.
出处
《中国肿瘤临床》
CSCD
北大核心
1996年第1期21-23,共3页
Chinese Journal of Clinical Oncology
关键词
肝肿瘤
诊断
甲胎蛋白
岩藻糖苷酶
血清
Primary hepatic cancer
Alpha-L-fucosidase(AFU) Alpha-fetoprotein(AFP)