二卤卡宾与羰基化合物反应的研究进展

Recent Development in Understanding the Reactions of Dihalocarbenes with Carbonyl Compounds

对近年来二卤卡宾与羰基化合物的反应机理研究进行了总结．指出二卤羰基Ｙｌｉｄｅ为反应的中间体，并对影响二卤羰基Ｙｌｉｄｅ的稳定性以及后续反应的因素如底物的立体效应、取代基的电子效应、Ｃａｐｔｏｄａｔｉｖｅ效应以及卤原子半径大小进行了讨论。

This review summarizes previous mechanistic studies on reactions of dihalocarbenes with carbonyl compounds where dihalocarbonyl Ylide was suggested to be the intermediate.The structural factors such as steric effects of substrates,electronic effects of substituents,Captodative effect of the carbonyl Ylide intermediate,and radius of the halogen atoms that influence the stabilities and conformations of the dihalocarbonyl Ylides and their following reaction pathways are also discussed.