乙酰基香豆素及其衍生物与吲哚的固相光反应研究

Studies on Solid State Photoreaction of Acetylcoumarin and Its Derivatives with Indole

乙酰基香豆素及其衍生物与吲哚的固相光反应研究杜大明，王永梅，孟继本，周秀中张慧萍（南开大学化学系，天津，３０００７１）（云南师范大学化学系）关键词香豆素，吲哚，固相光反应近年来固相光化学发展非常迅速，引起国内外学者的关注［１～３］．我们研究了异种分子...

The photochemical reaction of 3-acetylcoumarin and its 7-acetyloxy,7-benzoyloxy,6-bromo and 5,6-benzo derivatives with indole in solid state gave only condensation products,while 3.acetyl-6-nitrocoumarin with indole gave ring-cleavage decarbonyl addition product in the solid state,3-Acetylcoumarin and its derivatives with indole can not undergo photochmical reaction in solution.The solid-state photochemical reaction shows a high selectivity.The effect of the nature of substituent and the position of substitution were also investigated,the withdrawing substituent facilitate the photoreaction and there is a higher reactivity of acetyl at position 3 than at position 6 and 8.The structures of six new products were identified by IR, MS,￣1H NMR and elemental analvsis.