2003—2004年福建省流感暴发监测分析

Study on the Surveillance of Influenza Outbreaks in Fujian, China(2003—2004)

[目的]了解福建省流感流行动态,探索流行规律,为流感防治提供科学依据。[方法]进行流行病学调查,用MDCK细胞和鸡胚进行病毒分离,用血凝抑制实验对病毒株进行分型鉴定及血清流感抗体测定。[结果]2003—2004年我省共报告局部暴发流感疫情49起,发病3 088例,共采集咽拭子或漱口液标本360份,分离流感病毒阳性率25.8%(93/360)。其中甲3型88株(94.6%),乙型5株(5.3%)。2年共采集流感样患者急性期、恢复期血清各221份,其中甲3型抗体4倍增长阳性率58.4%(129/221),乙型抗体4倍增长阳性0.5%(11/221)。[结论]引起福建省2003—2004年流感暴发的毒株以甲3型为主,暴发的时间主要集中在每年的4月和9月。

[Objective] To study epidemiological trend of influenza for the disease control in Fujian （2003-2004）. [Methods] Through case epidemiologieal investigation and sample collection, influenza viruses were isolated by MDCK cells and embryonated eggs. The virus strains were identified and sera antibody was detected by hemagglutination inbibi tion （HI）. [Results] 49 influenza outbreaks with 3 088 cases were reported in Fujian. 93 viru,s strains were isolated from 360 throat swabs and positive rate was 25.8%. Among them, 88 strains were Type A H3N2 （94.6%） and 5 were Type B （5.4%）. There were double blood specimen from 221 influenza-like cases at acute and convalesce stage as well. The antibody positive rate of paired sera （4-fold rising）was 58.4% （129/221）for Type A H3N2, and 0.5% （11/221）Type B. [Conclusion] The main influenza virus is Type A H3N2 eaused most of influenza outbreaks in Fujian between 2003 and 2004, and the majority of them occurred in April and September.