超声背向散射积分评价颈动脉粥样硬化斑块的危险性

Assessment of Atherosclerotic Plaque Risk in Carotid Arteries U sing Ultrasound Integrated Backscatter

目的本研究通过测定颈动脉不同回声类型粥样硬化斑块背向散射积分(IBS)的变化特点,初步探讨其在评价颈动脉粥样硬化斑块危险性方面的价值。方法对30例急性脑梗死及30例无脑血管疾病患者的颈动脉硬化斑块进行IBS参数测定,对不同回声类型硬化斑块的IBS三项参数(PPI:最大值与最小值之差,AII:平均值,SDI:离散度)进行对比分析,采用TGC均值对AII进行标准化。结果(1)在均质性斑块中,弱、低及强回声斑块的标化AII呈递增趋势,分别为:(29.4±4.8)dB、(38.7±5.6)dB、(50.7±6.8)dB;非均质性斑块的标化AII变化较大,其PPI及SDI明显高于均质性斑块(P<0.001);(2)脑梗死组非均质性斑块及均质性弱回声斑块的检出率明显高于对照组(P<0.001),而均质性强回声斑块的检出率低于对照组。结论IBS参数为了解颈动脉硬化斑块的组织学特征提供了客观的定量依据,为预测颈动脉硬化斑块的危险性提供重要信息。

Objective This investigation aimed to find out the value of ultrasound intergrated backcatter（IBS） in assessing the atherosclerotic plaque risk in ceaotid arteries by measuring different echoes and the characteristics of IBS in carotid plagues.Methods IBS of atherosclerotic carotid plaque in 30 cases with acute cerebral infarction and 30 healthy subjects were measured,including PPI（peak-to-peak intensity）,AII （average image intensity） and SDI（standard deviation of image intensity）,AII （aerage image intensity） and SDI（standard deviation of image intensity）,AII values were standardized by the means of TGC values.Results （1） The standardized AII of homogeneous plagues in weak,low and strong echoes presnted an increasing trend,respectively：29.4±4.8dB,38.7±5.6dB and 50.7±6.8dB;the standardized AII of heterogeneous plaques changes considerably,PPI and SDI were echo in both homogeneous and heterogeneous plaques in the cerebral infarction group was significantly higher than that of the healthy control （P〈0.001）,while the detection rate of high echo of homogeneous plaques was relatively lower than that of the healthy control.Conclusions IBS might be considered as a sensitive and specific parameter to be a quantitative basis for estimating and predicting the plaque risks in atherosclerotic carotid arteries.