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COX-2和CD_(44)V6及MMP-9在胃癌中的表达及与胃癌淋巴结转移的关系

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摘要 本文检测胃癌组织中COX-2、CD44V6、MMP-9表达,了解三者表达的相互关系及与胃癌淋巴结转移的关系。作者采用免疫组化S-P法检测73例胃癌组织中COX-2、CD44V6、MMP-9的表达情况,并分析它们之间表达的相关性及与胃癌淋巴结转移的关系。结果显示,胃癌组织中COX-2表达和CD44V6、MMP-9表达呈正相关,胃癌组织中COX-2、CD44V6、MMP-9表达与胃癌淋巴结转移相关,COX-2可能上调CD44V6、MMP-9的表达促进胃癌的侵袭与转移。
出处 《中国医师杂志》 CAS 2005年第9期1257-1258,共2页 Journal of Chinese Physician
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