晚期妊娠引产临床观察

Clinical Study of Induced Labor in Late Pregnancy

目的比较米索前列醇(简称米索)、催产素、小剂量米索+催产素用于晚期妊娠引产的效果。方法100例孕37～42周的单胎头位产妇,均具有引产指征,随机分为A组(28例)、B组(35例)及C组(37例),分别给予阴道后穹隆置入米索、静滴催产素以及小剂量米索加催加素引产,比较三组宫颈评分、总产程、分娩方式、出血量、新生儿Apgar评分、药物副反应差异。结果C组分别与A、B组比较,平均引产成功率高,而平均总产程短、胎儿窘迫率、剖宫产率低(P<0.05),出血量、新生儿Ap gar评分比较无显著差异(P>0.05)。结论小剂量米索+催产素用于晚期妊娠引产安全有效。

Objective To compare the effect of misoprostol, oxytoein, combined application of low dose misoprostol and oxytocin in the induced labor in late pregnancy. Methods 100 cases of 37 to 42 weeks pregnaney with indication of indtteed labor were randomly divided into group A（n =28）, group B（ n = 35）, group C（ n = 37） anti treated with misoprostol in vaginal fiwnix, oxytncin IV drop, and combination of low dose misoprostol anti oxvtncin respectively. Comparative analysis was performed in terms of entire labor duration, deliver methods, bitted loss, Apgar scoring of neonate, and side-effect of drugs. Results Compared with group A anti B, group C showed no significant difference in ternrs of blood loss and neonate Apgar scoring, whereas demonstrated significantly higher induced rate, shorter entire labor duration, lower fetal distress rate and cesarean section rate. Conclusion Application of low dose ntisoprostol associated with oxvtocin is safe and effective in induced labor in late pregnancy.