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造血干细胞移植后抗感染治疗

Anti-imflammatory therapy after hematopoietic stem-cell transplantation
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摘要 感染是造血干细胞移植(HSCT)最常见的并发症,也是主要致死原因之一.近年来采用全环境保护及其预防措施,在一定程度上减少了移植后感染的发生率;同时由于诊断技术的发展,新型抗生素的不断推出,以及经验性治疗的早期应用等,显著降低了某些严重感染的病死率.然而,由于中、大剂量免疫抑制剂的使用,患者免疫功能缺陷,原发血液系统恶性疾病,大剂量化疗和(或)放疗的开展,中心静脉导管和静脉高营养的普遍应用,HSCT造血重建延迟或排斥以及并发移植物抗宿主病(GVHD)等诸多因素,使HSCT患者更易并发严重感染,成为影响HSCT患者预后的重要因素之一.
作者 黄晓军
出处 《临床药物治疗杂志》 2005年第5期4-7,共4页 Clinical Medication Journal
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参考文献8

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