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初诊2型糖尿病用胰岛素泵短期强化治疗与用磺脲类药物治疗的比较 被引量：1

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摘要 本研究是通过对新诊断的2型糖尿病患者随机平均分到胰岛素泵强化治疗组和磺脲类药物治疗组治疗后观察胰岛β细胞的功能,以进一步探讨早期胰岛素泵强化治疗对胰岛β细胞功能的影响,现报告如下.
作者 贡明贤 彭杰 莫英曼
机构地区 贵阳医学院附属医院内分泌科
出处 《贵州医药》 CAS 2005年第9期808-809,共2页 Guizhou Medical Journal
关键词 胰岛素泵强化治疗 2型糖尿病患者 短期强化治疗 磺脲类药物 药物治疗 胰岛β细胞功能 初诊 治疗组 治疗后
分类号 R587.1 [医药卫生—内分泌] R735 [医药卫生—肿瘤]
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参考文献6

  • 1Purrell oF, Rabuazza AM. Metabolic factors that affect beta-cell function and survival. Diabet Nutr Metab, 2000,13:84～91.
  • 2Sivitz WI. Lipotoxicity and glucotoxicity in type 2 diabetes. Effects on development and progression. Postgrad Med, 2001,109 : 55～64.
  • 3Del Prato S, Marchetti P, Bonadonna RC. Phasic insulin release and metabolic regulation in type 2 diabetes. Diabetes, 2002,51 suppl 1 : S109 ～ 116.
  • 4李延兵,翁建平,许雯,陈小华,廖志红,姚斌,邓婉萍,欧香忠,胡国亮.短期持续胰岛素输注治疗对初诊2型糖尿病患者胰岛β细胞功能的影响[J].中国糖尿病杂志,2003,11(1):10-15. 被引量：777
  • 5Hasan H, glaser B, Tunckale A, et al. Induction of longterm glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care,1997,20:1 353～1 356.
  • 6Yanbing Li,JianPing Weng. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of βcell function. Diabetes Care,2004,27:2 597～2 603.

二级参考文献10

  • 1Purrello F, Rabuazza AM. Metabolic factors that affect betacell function and survival. Diabet Nutr Metab, 2000, 13: 84-91.
  • 2Sivitz WI. Lipotoxieity and glueotoxieity in type 2 diabetes. Effects on development and progression. Postgrad Med, 2001,109: 55-59,63-64.
  • 3Lenhard M J, Reeves GD. Continous subcutaneous insulin infusion: a comprehensive review of insulin pump therapy. Arch Intern Med,2001,161: 2293-2300.
  • 4Dupuy O, Mayaudon H, Palou M, et al. Optimized transient insulin infusion in uneontrolled type 2 Diabetes : Evaluation of a pragmatie attitude. Diabet Med, 2000,26 : 371-375.
  • 5Valensi P, Moura I, Magoarou M,et al. Short-term effects of continuous subcutaneous insulin infusion treatment on insulin secretion in non-insulin-dependent overweight patients with poor glycaemic control despite maximal oral anti-diabetic treatment. Diabet Metab,1997,23: 51-57.
  • 6Lormeau B, Aurousseau MH, Valensi P, et al. Hyperinsulinemia and hypofibrinolysis: effects of short-term optimized glyeemic control with contineuous insulin infusion in type Ⅱ diabetie patients. Metabolism,1997,46: 1074-1079.
  • 7Ilkova H, Glaser B, Tunckale A, et al. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care, 1997,20:1353-1356.
  • 8Pratley RE, Weyer C. The role of impaired early insulin secretion in the pathogenesis of type II diabetes mellitus. Diabetologia 2001,44:929-945.
  • 9Del Prato S, Marchetti P, Bonadonna RC. Phasic insulin release and metabolic regulation in type 2 diabetes. Diabetes,2002, 51suppl 1: s109-116.
  • 10Kahn SE. The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus. Am J Med, 2000,108suppl 6a: 2s-8s.

共引文献776

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贵州医药
2005年 第9期

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